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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
32.12
Human Site:
S361
Identified Species:
58.89
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S361
W
R
D
P
K
S
G
S
W
Y
V
E
T
L
D
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Y226
L
C
A
M
L
K
Q
Y
A
D
K
L
E
F
M
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S361
L
R
D
P
K
S
G
S
W
Y
I
E
T
L
D
Dog
Lupus familis
XP_865164
414
45235
S360
W
R
N
T
K
S
G
S
W
Y
V
E
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
S384
M
R
N
T
K
R
G
S
W
Y
I
E
A
L
T
Rat
Rattus norvegicus
P55215
452
50709
S384
M
R
N
T
K
R
G
S
W
Y
I
E
A
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
S311
W
R
D
T
Q
S
G
S
W
Y
I
E
T
L
D
Chicken
Gallus gallus
Q98943
424
47941
S355
M
R
N
T
K
R
G
S
W
Y
I
E
A
L
T
Frog
Xenopus laevis
P55866
282
32106
C231
S
W
F
I
Q
S
L
C
K
M
I
K
L
Y
G
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
S376
W
R
D
T
E
A
G
S
W
Y
V
E
N
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
L272
K
K
Y
D
L
L
T
L
L
T
F
V
N
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
S435
W
R
N
S
A
R
G
S
W
F
I
Q
A
V
C
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
S375
W
R
N
A
E
R
G
S
W
F
I
Q
A
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
0
86.6
86.6
N.A.
53.3
53.3
N.A.
80
53.3
6.6
73.3
N.A.
0
N.A.
33.3
40
P-Site Similarity:
100
0
93.3
93.3
N.A.
66.6
66.6
N.A.
93.3
66.6
26.6
86.6
N.A.
6.6
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
0
8
0
0
0
39
0
0
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
0
31
8
0
0
0
0
0
8
0
0
0
0
39
% D
% Glu:
0
0
0
0
16
0
0
0
0
0
0
62
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
16
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
62
0
0
0
0
% I
% Lys:
8
8
0
0
47
8
0
0
8
0
8
8
0
0
0
% K
% Leu:
16
0
0
0
16
8
8
8
8
0
0
8
8
70
0
% L
% Met:
24
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
47
0
0
0
0
0
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
8
0
0
0
0
16
0
8
0
% Q
% Arg:
0
77
0
0
0
39
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
0
8
0
39
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
47
0
0
8
0
0
8
0
0
31
0
31
% T
% Val:
0
0
0
0
0
0
0
0
0
0
24
8
0
8
0
% V
% Trp:
47
8
0
0
0
0
0
0
77
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
62
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _